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  hum-molgen: bioinformatic tools  
 

selection of important external bioinformatic tools

 
             
 
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 Tools for Genetic Data Analysis
 

EasyLinkage
Lindner TH, et al. easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses. Bioinformatics. 2005 Feb 1;21(3):405-7.

Genetic Power Calculator
Purcell S, et al. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics. 2003 Jan;19(1):149-50.

GOLD
Abecasis GR, et al. GOLD--graphical overview of linkage disequilibrium. Bioinformatics. 2000 Feb;16(2):182-3.

Haploview
Barrett JC, et al. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005 Jan 15;21(2):263-5.

HapMap
The International HapMap Consortium. The International HapMap Project. Nature. 2003 Dec 18;426(6968):789-96.

MDR
Hahn LW, et al. Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics. 2003 Feb 12;19(3):376-82.

PLINK
Purcell S, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007 Sep;81(3):559-75.

SNPstats
Solé X, et al. SNPStats: a web tool for the analysis of association studies. Bioinformatics. 2006 Aug 1;22(15):1928-9.

Structure
Pritchard JK, et al. Inference of population structure using multilocus genotype data. Genetics. 2000 Jun;155(2):945-59.

 
 Genomics Tools
 

BioMart
Durinck S, et al BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis. Bioinformatics. 2005 Aug 15;21(16):3439-40.

Galaxy
Giardine B, et al. Galaxy: a platform for interactive large-scale genome analysis. Genome Res. 2005 Oct;15(10):1451-5.

Genecards
Safran M, et al. Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE. Nucleic Acids Res. 2003 Jan 1;31(1):142-6.

KEGG pathways
Kanehisa M, et al. KEGG for linking genomes to life and the environment. Nucleic Acids Res. 2008 Jan;36(Database issue):D480-4.

NCBI BLAST
Wheeler DL, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2008 Jan;36(Database issue):D13-21.

NCBI GEO
Wheeler DL, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2008 Jan;36(Database issue):D13-21.

OMIM
Wheeler DL, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2008 Jan;36(Database issue):D13-21.

SymAtlas
Su AI, et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6062-7.

UCSC Blat
Karolchik D, et al. The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res. 2008 Jan;36(Database issue):D773-9.

UniHI
Chaurasia G, et al. UniHI: an entry gate to the human protein interactome. Nucleic Acids Res. 2007 an;35(Database issue):D590-4.

 Human Genome Browsers
 

UCSC genome browser
Karolchik D, et al. The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res. 2008 Jan;36(Database issue):D773-9.

Ensembl genome browser
Flicek P, et al. Ensembl 2008. Nucleic Acids Res. 2008 Jan;36(Database issue):D707-14.

NCBI genome browser
Wheeler DL, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2008 Jan;36(Database issue):D13-21.

 
 Genotyping Design and Analysis Tools
 

F-SNP
Lee PH, et al. F-SNP: computationally predicted functional SNPs for disease association studies. Nucleic Acids Res. 2008 Jan;36(Database issue):D820-4.

NEBcutter
Vincze T, et al. NEBcutter: A program to cleave DNA with restriction enzymes. Nucleic Acids Res. 2003 Jul 1;31(13):3688-91.

novoSNP
Weckx S, et al. novoSNP, a novel computational tool for sequence variation discovery. Genome Res. 2005 Mar;15(3):436-42.

PIRA
Ke X, et al. PIRA PCR designer for restriction analysis of single nucleotide polymorphisms. Bioinformatics. 2001 Sep;17(9):838-9.

Primer3
Rozen S, et al. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol. 2000;132:365-86.

WASP
Wangkumhang P, et al. WASP: a Web-based Allele-Specific PCR assay designing tool for detecting SNPs and mutations. BMC Genomics. 2007 Aug 14;8:275.

 
 Extended Lists of Bioinformatic Resources
 

NAR database issue, 2008

NAR web server issue, 2007

NAR database issue, 2007

 
 
 
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