HUM-MOLGEN DIAGnostics/Clinical
Research
5/1/96
Chromosomal translocations/reply
addendum
Date sent: 3-JAN-1996 09:05:04
> >Where can I find a catalogue of described chromosome translocations?
> > >COLD SPRING HARBOR LABORATORY
>1 Bungtown Road
>Cold Spring Harbor, NY 11724
(largely contributed by Martin Kennedy)
For cancer the definitive source is Mitelman's (4th ed - though may
be a more recent edition) "Catalog of chromosome aberrations in cancer",
1991, Wiley Liss ISBN 0-471-56087-1
The hard-copy Human Gene Mapping publications have tables of translocations;
the last one we have is HGM 11 (1991). Cytogenet. Cell Genet. 58:1-2200.
I think there may have been one more book publication, but I believe that
the electronic version (GDB - see below) is now the exclusive repository
of this information.
Also a review on CT was published in Nature, 372, 143-149, 1994.
Alternatively, try the following online sources:
CAD
The Chromosome Abnormality Database (CAD) stores records of human chromosome
abnormalities, and can be freely searched. Established in early 1991, the
CAD contains records of acquired and constitutional chromosome abnormalities
from cytogenetics laboratories throughout the United Kingdom. The database
includes information on the availability of cell lines and other stored
material.
WWW: http://www.hgmp.mrc.ac.uk/local-data/Cad_Preamble.html
Gopher: gopher.hgmp.mrc.ac.uk (go to "HGMP Databases/" directory).
GDB (Genome Database)
A comprehensive, fully searchable repository of human gene mapping
information, cross referenced to other relevant databases including OMIM
and the Genome Sequence Data Bank. May be worth searching for info on specific
translocations.
WWW: http://gdbwww.gdb.org/gdbhome.html
Gopher: gopher.gdb.org (in "Search Databases at Hopkins"
directory)
E-mail server: mailserv@gdb.org
Anonymous ftp: ftp://ftp.gdb.org/
OMIM (Online Mendelian Inheritance in Man)
Subtitled "A catalog of human genes and genetic disorders",
this is the electronic form of Victor McKusick's extraordinary compilation,
Mendelian Inheritance in Man (McKusick, 1994; Pearson et al., 1994). It
contains a wealth of data on human genetic traits and inheritance patterns,
and each disease entry consists of a comprehensive literature review with
full cross referencing to other relevant databases.
WWW: http://gdbwww.gdb.org/gdbhome.html
Gopher: gopher.gdb.org (in "Search Databases at Hopkins"
directory)
E-mail server: mailserv@gdb.org