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| HUM-MOLGEN -> Events | Search | Write an announcement | ||||||||||||||||
Courses and Workshops by continent |
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| September, 07 2008 |
your calendar for events in genetics, biotechnology and medicine |
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| Europe | November 17-19, 2008 Biotechnology: 14th Annual International Partnering Conference BIO-Europe 2008 |
EBD Group, Mannheim/Heidelberg, Germany | ||||||||||||||
| 29 September to 2 October 2008 Computational Genetics / Bioinformatics: First Announcement Summer School on Systems Biology for Medical Applications |
Costa Adeje Gran Hotel, Tenerife, Spain | |||||||||||||||
| from 8th November to 11st November 2008 Ethics and Government: First Announcement Peer Review in Theory and Practice: |
The European School of Genetic Medicine, EuroMediterranean University Centre of Ronzano, Bologna, ITALY | |||||||||||||||
| 19-28 April 2009 Genetics: A wellcome Trust Advanced Course Microarrays:Methods and Applications for Genome Analysis |
Wellcome Trust Advanced Courses, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK | |||||||||||||||
| 17-26 June 2009 Genetics: A wellcome Trust Advanced Course Functional Genomics and Systems Biology |
Wellcome Trust Advanced Courses, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK | |||||||||||||||
| from 23rd October 2008 to 27th October 2008 Genetics: First Announcement Course in Integration of cytogenetics, microarrays and massive sequencing in biomedical and clinical research |
The European School of Genetic Medicine, EuroMediterranean University Centre of Ronzano, Bologna, ITALY | |||||||||||||||
| 28th May - 1st June 2009 Others: CALL FOR ABSTRACTS Mutation Detection 2009: 10th International Symposium on Mutations in the Genome |
Coral Beach Hotel & Resort, Paphos, Cyprus | |||||||||||||||
| Sep 8 2008 Others: First Announcement Building the eCTD |
Drug Information Association, Dorint Praha Don Giovanni Hotel, Vinohradska 157a, Prague, Czech Republic | |||||||||||||||
| Sep 25 2008 Others: First Announcement European Regulatory Affairs |
Drug Information Association, Frankfurt am Main, Germany. | |||||||||||||||
| Sep 22 2008 Others: First Announcement Medical Approach in Diagnosis and Management of ADRs |
Drug Information Association, SAS Radisson Hotel Boulogne, Paris, France | |||||||||||||||
| Sep 22 2008 Others: First Announcement Essentials of Clinical Study Management |
Drug Information Association, SAS Radisson Hotel Boulogne, Paris, France. | |||||||||||||||
| 09 – 11 February 2009 Others: Kevin Ryan, Course Director STABILITY TESTING OF PHARMACEUTICALS |
ROYAL PHARMACEUTICAL SOCIETY OF GREAT BRITAIN, Cambridge | |||||||||||||||
| Monday 24 – Wednesday 26 November 2008 Others: N/a Tabletting Technology for the Pharmaceutical Industry |
Moller Centre, Cambridge | |||||||||||||||
| 10/20/08 Others: Training seminar; Limited seats available! Medical Devices: EU Directives, Guidance, CE Marking and ISO Standard Certifications |
The Center for Professional Innovation & Education, Dublin, Ireland | |||||||||||||||
| Sep 16 2008 Pharma Development and Business: First Announcement EudraVigilance: Medicinal Product Dictionary |
Drug Information Association, EMEA, 7 Westferry Circus , Canary Wharf, London, UK | |||||||||||||||
| Sep 17 2008 Pharmacogenetics / Pharmacogenomics: First Announcement Eudravigilance - Electronic Reporting of ICSRs in the EEA |
Drug Information Association, EMEA, Canary Wharf, London, UK | |||||||||||||||
| Sep 22 2008 Pharmacogenetics / Pharmacogenomics: First Announcement Eudravigilance - Electronic Reporting of ICSRs in the EEA |
Drug Information Association, EMEA, Canary Wharf, London, UK | |||||||||||||||
| Monday 20-Tuesday 21 October 2008 Pharmacology and Toxicology: N/a FIP/SIG Workshop: Special dosage forms – What’s new with in vitro drug release? |
Royal Pharmaceutical Society of Great Britain, London | |||||||||||||||
| 20th and 21st January 2009 Pharmacology and Toxicology: Training ADME PK/TK and Drug Metabolism in Drug Discovery and Development |
Mondial Research Group, Brussels , Belgium | |||||||||||||||
| North America | November 6-7, 2008 Biotechnology: IBC Training Course: Stability & Specifications for Biological and Biotechnology Derived Products |
IBC Professional Training Academy, San Diego, CA | ||||||||||||||
| November 6 - 19 2008 Cell and Molecular Biology / Anatomy: Cold Spring Harbor Laboratory Course PROTEOMICS |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| October 13 - 28, 2008 Cell and Molecular Biology / Anatomy: Cold Spring Harbor Laboratory Course X-RAY METHODS IN STRUCTURAL BIOLOGY |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| November 18-19, 2008 Computational Genetics / Bioinformatics: Cold Spring Harbor Laboratory Course GENOME ACCESS COURSE |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| November 6 - 19 2008 Computational Genetics / Bioinformatics: Cold Spring Harbor Laboratory Course PHAGE DISPLAY OF PROTEINS & PEPTIDES |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| November 5 - 11 2008 Computational Genetics / Bioinformatics: Cold Spring Harbor Laboratory Course COMPUTATIONAL & COMPARATIVE GENOMICS |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| October 19 - November 1, 2008 Computational Genetics / Bioinformatics: Cold Spring Harbor Laboratory Course IMMUNOCYTOCHEMISTRY, IN SITU HYBRIDIZATION & LIVE CELL IMAGING |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| October 15-28, 2008 Computational Genetics / Bioinformatics: Cold Spring Harbor Laboratory Course PROGRAMMING FOR BIOLOGY |
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York USA | |||||||||||||||
| October 15-18, 2008 Genetics: First Announcement, accepting applications Methods in Human Embryonic Stem Cell Research |
The Jackson Laboratory, The Jackson Laboratory, Bar Harbor, ME | |||||||||||||||
| October 14, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: 90 Minute Accredited Online Training CSOs: Are They Right for You? |
The Center for Professional Advancement, 90 Minute Accredited Online Training | |||||||||||||||
| December 4, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: 90 Minute Accredited Online Training Natural Ingredients in Formulating Skin Care Products |
The Center for Professional Advancement, 90 Minute Accredited Online Training | |||||||||||||||
| October 30, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: 90 Minute Accredited Online Training Protecting the Food Supply from Terrorists: What the Food Industry Needs to Know |
The Center for Professional Advancement, 90 Minute Accredited Online Training | |||||||||||||||
| September 16, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: An Online Training Course Lyophilization 101: Principles, Physical Properties and Characterization Techniques |
The Center for Professional Advancement, An Online Training Format | |||||||||||||||
| November 4, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: An Online Training Course 21 CFR Part 11: Strategies for Cost Effective Compliance Using a Risk-based Approach |
The Center for Professional Advancement, An Online Training Format | |||||||||||||||
| September 25, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: An Online Training Course Creating Fragrance for a Green World |
The Center for Professional Advancement, An Online Training Format | |||||||||||||||
| September 18 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: An Online Training Course Global Cosmetic Regulations: Going Green |
The Center for Professional Advancement, An Online Training Format | |||||||||||||||
| October 2, 2008 at 11:00 a.m. - 12:30 p.m. (EST–New York time) Others: An Online Training Course Assuring Your Supply Chain through Supplier Qualification |
The Center for Professional Advancement, An Online Training Format | |||||||||||||||
| 09/15/08-09/16/08 Others: Clincal Clinical Cost Containment |
ExlPharma, Philadelphia, PA | |||||||||||||||
| Sep 8 2008 Others: First Announcement Clinical Statistics for Nonstatisticians |
Drug Information Association, Four Points by Sheraton Washington DC Downtown, Washington, DC, USA | |||||||||||||||
| Sep 22 2008 Others: First Announcement 2nd DIA Conference: Oligonucleotides-based Therapeutics Conference |
Drug Information Association, Fairview Park Marriott, Falls Church, VA, USA. | |||||||||||||||
| Sep 15 2008 Others: First Announcement The Leadership Experience |
Drug Information Association, Hyatt Regency Chicago, Chicago, IL, USA | |||||||||||||||
| Sep 15 2008 Others: First Announcement Clinical Project Management |
Drug Information Association, DIA, Horsham, PA, USA | |||||||||||||||
| September 29-30, 2008 Others: IBC Training Course: Validation of Analytical Methods |
IBC Professional Training Academy, San Francisco, CA | |||||||||||||||
| 2008-10-27 Others: Registration is now open cGMP Training Seminar |
SPI USA, Inc., Bloomington, Indiana | |||||||||||||||
| Nov 6-7 Others: Registration is now open US Medical Devices Seminar |
SPI USA, Inc., Bloomington, Indiana | |||||||||||||||
| 10/6/08 Others: Training seminar; Limited seats available! Patent & Other Intellectual Property Law for the Life Sciences Industry |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/1/08 Others: Training seminar; Limited seats available! Process Validation for Medical Devices |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/6/08 Others: Training seminar; Limited seats available! Design Control for Medical Device Professionals |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/14/08 Others: Training seminar; Limited seats available! How to Implement Risk Management Principles and Activities Within a Quality Management System |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/1/08 Others: Training seminar; Limited seats available! Technical Writing for the Pharmaceutical, Medical Device, and Biotech Industries |
The Center for Professional Innovation & Education, Dublin, Ireland | |||||||||||||||
| 10/14/08 Others: Training seminar; Limited seats available! The EU Clinical Trial Directive |
The Center for Professional Innovation & Education, Dublin, Ireland | |||||||||||||||
| 10/15/08 Others: Training seminar; Limited seats available! Current Good Laboratory Practices & Current Good Manufacturing Practices - A Basic Primer |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 10/15/08 Others: Training seminar; Limited seats available! cGMP for Quality Assurance and Quality Control of Pharmaceuticals, Biopharmaceuticals, and Biologics |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/16/08 Others: Training seminar; Limited seats available! Effective Quality Assurance Auditing for FDA Regulated Industries |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/16/08 Others: Training seminar; Limited seats available! European Filing & Registration Procedures |
The Center for Professional Innovation & Education, Dublin, Ireland | |||||||||||||||
| 10/16/08 Others: Training seminar; Limited seats available! Practical Methods for Project Management |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/20/08 Others: Training seminar; Limited seats available! Stability Programs for Product Shelf Life – From Development to Approval |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/3/08 Others: Training seminar; Limited seats available! Practical Methods for Project Management |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 10/20/08 Others: Training seminar; Limited seats available! Good Clinical Practices (GCPs) |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/20/08 Others: Training seminar; Limited seats available! Effective Document Management for the Pharmaceutical, Biotech & Medical Device Industries |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/22/08 Others: Training seminar; Limited seats available! Dermatological Product Development |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/23/08 Others: Training seminar; Limited seats available! Adverse Drug Events – Reporting & Regulatory Requirements |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/23/08 Others: Training seminar; Limited seats available! Introduction to Effective Medical Writing |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/27/08 Others: Training seminar; Limited seats available! Preparation of FDA Submissions (INDs, NDAs, BLAs, ANDAs, Post-Approval Supplements) and Communicating with the FDA |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/3/08 Others: Training seminar; Limited seats available! Marketing, Advertising and Promotion of Pharmaceuticals and Medical Devices |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 11/4/08 Others: Training seminar; Limited seats available! Latin America – Understanding Regulatory Compliance Requirements |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/60/8 Others: Training seminar; Limited seats available! Japan - Regulatory Filing Requirements and Compliance Processes for Life Sciences |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/4/08 Others: Training seminar; Limited seats available! Cleanroom Microbiology for the Non-Microbiologist |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/5/08 Others: Training seminar; Limited seats available! How to Develop an Effective Complaint Handling and Post Market Surveillance Program for Drugs and Devices |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 11/6/08 Others: Training seminar; Limited seats available! Sterilization Procedures: Technology, Equipment and Validation |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/29/08 Others: Training seminar; Limited seats available! Best Practices for an Effective Cleaning Validation Program |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 10/30/08 Others: Training seminar; Limited seats available! Quality Systems Regulation for the Medical Device & Biotech Industries |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/6/08 Others: Training seminar; Limited seats available! Pharmaceutical Production Batch Record Review |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 11/10/08 Others: Training seminar; Limited seats available! Analytical Method Validation for Pharmaceutical, Biopharmaceutical, and Biologics Quality Control |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/10/08 Others: Training seminar; Limited seats available! How to Develop an Effective Complaint Handling and Post Market Surveillance Program for Drugs and Devices |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/1/08 Others: Training seminar; Limited seats available! Overview of FDA Regulatory Compliance for Medical Devices |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/1/08 Others: Training seminar; Limited seats available! Clinical Trials Design for Medical Devices |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/1/08 Others: Training seminar; Limited seats available! Current Good Laboratory Practices & Current Good Manufacturing Practices - A Basic Primer |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 12/2/08 Others: Training seminar; Limited seats available! Selecting and Managing CROs |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/15/08 Others: Training seminar; Limited seats available! Preparing the CMC Section for NDAs/INDs/CTDs |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/8/08 Others: Training seminar; Limited seats available! Pharmaceutical Maintenance Management- Understanding cGMPs |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/4/08 Others: Training seminar; Limited seats available! Drug Master Files (DMFs) - Understanding and Meeting Your Regulatory and Processing Responsibilities |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/3/08 Others: Training seminar; Limited seats available! Good Monitoring Practices for Medical Devices |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/2/08 Others: Training seminar; Limited seats available! Effective Document Management for the Pharmaceutical, Biotech & Medical Device Industries |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/3/08 Others: Training seminar; Limited seats available! Software Development for Medical Device Professionals |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/3/08 Others: Training seminar; Limited seats available! Reporting Failure Investigations and Process Deviations |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/4/08 Others: Training seminar; Limited seats available! Perspectives on Good Laboratory and Manufacturing Practices for Pre-Clinical Testing: Compliance, QA and Audit |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 12/8/08 Others: Training seminar; Limited seats available! Effective Risk-Based Applications of Drug cGMPs and Validation Requirements for Cosmetics and OTC Drug Products |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/8/08 Others: Training seminar; Limited seats available! Technical Writing for the Pharmaceutical, Medical Device, and Biotech Industries |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/20/08 Others: Training seminar; Limited seats available! FDA Inspections of Clinical Data Systems |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/8/08 Others: Training seminar; Limited seats available! The CTD/eCTD: Building the Marketing Application Throughout Clinical Development |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/10/08 Others: Training seminar; Limited seats available! Generic Drug Approvals: Preparing an ANDA for First-Cycle Approval |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/1/08 Others: Training seminar; Limited seats available! CMC Regulatory Compliance for Biopharmaceuticals and Biologics |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/11/08 Others: Training seminar; Limited seats available! Understanding Regulatory & Clinical Information Systems During Product Development |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/19/08 Others: Training seminar; Limited seats available! Introduction to Molecular Biology Techniques – Applications in the Biotechnology and Pharmaceutical Industries |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/19/08 Others: Training seminar; Limited seats available! Project Management for the Phase 3 and LCM (Life Cycle Management) of the Drug Development Process |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/19/08 Others: Training seminar; Limited seats available! FDA Inspections: What To Expect and How To Prepare |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/19/08 Others: Training seminar; Limited seats available! Selecting and Managing CROs |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 11/10/08 Others: Training seminar; Limited seats available! Aseptic Processing in the Manufacture of Biotech and Pharmaceutical Products |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/10/08 Others: Training seminar; Limited seats available! Writing Effective Standard Operating Procedures and Other Process Documents |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 12/12/08 Others: Training seminar; Limited seats available! How to Prepare for a Systems-based Inspection – Understanding the FDA’s Risk-based Inspections Approach and Ensuring Compliance |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/13/08 Others: Training seminar; Limited seats available! Effective Laboratory Safety Management |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/13/08 Others: Training seminar; Limited seats available! Medical Devices: EU Directives, Guidance, CE Marking and ISO Standard Certifications |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 12/12/08 Others: Training seminar; Limited seats available! Stability Testing of Proteins, Peptides & Other Biomolecules |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/13/08 Others: Training seminar; Limited seats available! Writing in the Regulated Environment When English Is Your Second Language |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 11/17/08 Others: Training seminar; Limited seats available! Drug Master Files (DMFs) - Understanding and Meeting Your Regulatory and Processing Responsibilities |
The Center for Professional Innovation & Education, Berlin, Germany | |||||||||||||||
| 11/17/08 Others: Training seminar; Limited seats available! Comprehensive Overview of FDA Regulatory Compliance for Drugs and Biotech Products |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 11/17/08 Others: Training seminar; Limited seats available! Project Management for Phase 1 & 2 Clinical Trials |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 10/6/08 Others: Training seminar; Limited seats available! Writing Effective Standard Operating Procedures and Other Process Documents |
The Center for Professional Innovation & Education, Dublin, Ireland | |||||||||||||||
| 11/17/08 Others: Training seminar; Limited seats available! The Drug Development Process - From Discovery to Commercialization |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| 08/11/08 Others: Training seminar; Limited seats available! Japan - Regulatory Filing Requirements and Compliance Processes for Life Sciences |
The Center for Professional Innovation & Education, Costa Mesa, CA | |||||||||||||||
| 10/1/08 Others: Training seminar; Limited seats available! Software Development for Medical Device Professionals |
The Center for Professional Innovation & Education, Malvern, PA | |||||||||||||||
| Sep 8 2008 Pharma Development and Business: First Announcement Drug Safety Surveillance and Epidemiology |
Drug Information Association, Four Points by Sheraton, Washington DC, USA | |||||||||||||||
| Sep 15 2008 Pharma Development and Business: First Announcement Fundamentals of Clinical Research Monitoring |
Drug Information Association, Four Points by Sheraton Washington DC Downtown | |||||||||||||||
| October 23-24, 2008 Pharma Development and Business: IBC Training Course: Production Process Deviation: Strategies for Investigation |
IBC Professional Training Academy, Boston, MA | |||||||||||||||
| October 16-17, 2008 Pharma Development and Business: IBC Training Course: Bioassay Method Development & Validation |
IBC Professional Training Academy, Research Triangle Park, NC | |||||||||||||||
| Sep 15 2008 Pharmacology and Toxicology: First Announcement Regulatory I: The IND Phase |
Drug Information Association, Park Hyatt Philadelphia at the Bellevue, Philadelphia, PA, USA | |||||||||||||||
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