- |
Advancing Spinal Research Stimulates New Clinical Trial Guidelines
Four papers to be published online address the need for a principled set of guidelines for clinical trials in patients with spinal damage.
|
- |
Exploitation Of Race As A Marketing Tool?
The obstacles facing the development of genetics-based personalized medicine are described online.
|
- |
Standardized Methods Improve Cancer Diagnosis
A set of guidelines for pathologists that may greatly improve the diagnosis of malignant lymphomas has been published online.
|
- |
Islet Transplantation For Diabetes: Failing To Deliver?
The promise of islet transplantation to treat diabetes has not yet been fully realised.
|
- |
Synchronized Sleeping In The Brain
Waking experiences are replayed in multiple parts of the brain in a coordinated fashion during sleep.
|
- |
Humans Follow The Scent
The human sense of smell may be better than previously thought.
|
- |
Sensing Fungal Infections
Two studies demonstrate the importance of a host protein in recognizing the presence of fungal infections.
|
- |
How Shigella Causes Dysentery
A report explores how shigella bacteria survives and spreads in the gut to cause dysentery.
|
- |
Lightning Strikes Twice For Milk Drinkers
The ability of Africans and Europeans to digest milk as adults is analyzed.
|
- |
Malaria Parasite Diversity
Three studies independently characterize the genetic diversity of the parasite that causes malaria.
|
- |
Scientists Share Thoughts On Animal Research
An anonymous online poll of nearly 1700 researchers has revealed intriguing insights into scientists' views on the use of animals in research.
|
- |
Cellular 'Dustbin' Modelled
A detailed model of the phagosome, the cellular 'dustbin' that engulfs and destroys foreign matter, is unveiled.
|
- |
Protein Blocks Brain Tumour Growth
A protein that blocks the growth of aggressive human brain tumours in a mouse model has been identified.
|
- |
Navigating The Mouse Brain
The comprehensive digital map of gene expression in the mouse brain will have an impact on the fields of neuroscience and mammalian genomics alike.
|
- |
Key Influenza Virus Molecule Visualised
Researchers have visualised the structure of the influenza A virus nucleoprotein.
|
- |
Carbon Dioxide Receptors And Malaria
The discovery of a pair of receptors that enable fruit flies to sense carbon dioxide (CO2) could boost the development of a new type of mosquito repellent.
|
- |
Botulinum Toxin Structure Unveiled
The structure of botulinum toxin B bound to one of its receptor is revealed.
|
- |
A Two Base Pair Deletion In The PQBP1 Gene Is Associated With Microphthalmia, Microcephaly, And Mental Retardation
Mutations in PQBP1 are associated with an S-XLMR phenotype including microphthalmia, thereby further extending the clinical spectrum of phenotypes associated with PQBP1 mutations.
|
- |
Changing Rates Of Genetic Subtypes Of Prader–Willi Syndrome In The UK
First report of a greater proportion (50%) of those with Prader–Willi Syndrome (PWS) due to maternal uniparental disomy (mUPD) in children presently under 5 years living in the UK.
|
- |
Molecular Genetic Analysis Of The Human Dihydrofolate Reductase Gene
Subjects were screened for the 9-bp repeat (n=417), as well as the recently reported 19-bp deletion in intron 1 (n=330) of the human dihydrofolate reductase (DHFR) gene, and their associations assessed with plasma tHcy, serum and RBC folate levels.
|
- |
The Single-Nucleotide Polymorphism 309 In The MDM2 Gene Contributes To The Li–Fraumeni Syndrome And Related Phenotypes
The higher prevalence of MDM2 SNP309 homozygous G/G carriers in the TP53-negative group suggests that this allele contributes to cancer susceptibility in LFS and LFS-related families.
|
- |
Review Article: Implication Of Abnormal Epigenetic Patterns For Human Diseases
New insights on the mechanisms by which epigenetic machinery proteins regulate gene expression.
|
- |
Mutation Prevents Pain
A mutation in one key gene can rob people of their ability to experience pain.
|