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A New Fanconi Anaemia Target
The identification of a second protein target for modification by the Fanconi anaemia (FA) complex, which is important in DNA repair, is reported.
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Standards For The Analysis Of Metagenomes
Simulated datasets for the evaluation of metagenomic analysis programs are presented.
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Engineering Diverse Sets Of Drug Sensitive Proteins
A paper describes a general approach to genetically engineer proteins that are regulated by small chemical drugs.
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Ancient Diversity
An ancient enzyme drives diversification of immune receptors in lampreys, and resembles an enzyme with a similar function in mammals.
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New Player In Inflammatory 'Shutdown'
Scientists show that a protein within immune cells stands poised to dampen inflammation.
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New Genetic Risk Factor For Type 2 Diabetes
Variation in the gene called CDKAL1 is associated with risk of developing type 2 diabetes.
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The Immune System And Susceptibility To Cancer
Variation in a genetic element that regulates the expression of the gene encoding caspase-8 (CASP8) is associated with differential susceptibility to several different cancers.
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Chromatin Link To Mental Retardation
A protein previously implicated in mental retardation has now been shown to influence gene expression by modifying histones.
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New Hypothesis For Amyloid Disease
Degenerative diseases such as Alzheimer's, Parkinson's and type 2 diabetes may share common structural features at the molecular level.
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Life Without Dad
Genomic imprinting is not always essential for seed development.
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Mice And Easy Memory Recovery
Long-term memories lost after brain damage can be restored in mice.
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Neuronal Imbalance May Contribute To Addiction
An imbalance between neuronal excitation and inhibition may contribute to the early stages of addiction.
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Enzyme Curtails Allergic Reaction To Chitin
Chitin, the main component of arthropod exoskeletons, elicits an innate allergic response in mice that can be controlled by a host enzyme.
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New Treatment For Muscular Dystrophy And Cystic Fibrosis
Mouse study suggests that a drug that allows cells to ignore a particular type of disease-causing mutation may ease the symptoms of Duchenne muscular dystrophy (DMD).
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