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Household Allergens Make Skin Vulnerable To Eczema
Dust mite and cockroach allergens aggravate the symptoms of eczema and similar diseases by disrupting skin barrier function.
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Autoimmunity Affected By More Than A Defective Immune System
Research suggests that autoimmunity is linked to defective developmental biology as well as a defective immune system.
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Chemical Treatment Of Neurons Makes Them Light Sensitive
A chemical treatment that makes neurons light responsive is described.
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Bone Marrow Nurturers
Researchers have identified a new cell residing in bone marrow that provides an essential survival factor for antibody-producing B cells.
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Multi-Tasking Sensor Of Immune 'Danger'
Data explaining how a single sensor of 'danger' manages to activate two distinct host immune defense signaling pathways is presented.
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Mitochondrial DNA Deletions Affect Lifespan
Large DNA deletions in mitochondria are associated with premature ageing in mice
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Genetic Variants Predisposing To Coeliac Disease
Scientists have identified variants in seven genomic regions that predispose to coeliac disease.
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Pathway Influences Human Hair Growth And Texture
Researchers have identified the genetic basis of two related but clinically distinct forms of inherited hair loss.
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Altered Stem Cells Accelerate Ageing
Study provides a mechanism by which the mutant protein Progerin contributes to the premature ageing disease Hutchinson-Gilford Progeria Syndrome (HGPS), and implications for our understanding of normal ageing.
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Twist Mediates Hypoxia-Driven Tumour Metastasis
Study identifies a pathway that could be active in several types of cancer, and the importance of using certain protein inhibitors for tumour treatment.
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Drug Detective Kit For The Cell's Powerhouse
A large-scale analysis of the effects of almost 2,500 drugs and natural products on mitochondria promises to become invaluable to scientists seeking new ways to tackle diabetes, neurodegeneration and even ageing.
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Building A Picture Of Sight
A device that can 'read' the brain and produce a picture of a person's visual experience could soon become a reality.
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Turning Off 'Stemness' In Skin Cells
Researchers have discovered the switch mechanism responsible for imposing the molecular boundary between the proliferating basal cells and terminally differentiating outer skin cells.
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Targeting Psychosis
A pair of receptors in the brain that react to hallucinogenic drugs are identified as a potential target for the treatment of psychosis.
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