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Exploring Exploration
Scientists show that a gene regulating dopamine breakdown is predictive of how likely people are to explore alternative strategies when uncertain about current strategy.
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The Immunology of Obesity
The potential mechanism by which chronic, mild inflammation of fat tissue in obese patients promotes the onset of diabetes, is reported in a series of studies published online.
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Why Did the HIV Vaccine STEP Trial Fail?
Two papers rule out a leading explanation for the failure of the recent HIV STEP trial which represented a serious blow to the development of an AIDS vaccine.
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Cell Source Matters for In Vitro Bone Growth
The type of cell used to grow bone for tissue replacement in the lab makes a difference to the properties of the resulting material.
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Suppressor Immune Cells: Friends or Foes?
Regulatory T (Treg) cells, which are essential to prevent catastrophic autoimmunity in mice and humans, can in some cases convert into inflammatory T cells capable of exacerbating autoimmunity.
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A Genetic Susceptibility Locus for Follicular Lymphoma
A common genetic variant is associated with risk for follicular lymphoma (FL).
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Chromosomes, Know Your Place
A catalogue of factors that help to keep the order of genes on chromosomes 'in their place' and so prevent genomic instability is revealed.
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Alzheimer's Gene Linked to Neurotransmitter Release
A gene best known for its link to Alzheimer's disease is now shown to be essential for regulating neurotransmitter release.
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Looking for Clues to Extending Life
Scientists discuss recent progress in mammalian sirtuin research and what role these enzymes may have in age-related diseases and how long we live.
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Live Mice from Fibroblast
Stem cells induced from somatic cells can be as pluripotent as stem cells extracted from embryos.
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New Function for Classic Tumour Suppressor Protein
The tumour suppressor protein p53 may have a previously unappreciated role in the processing of miRNAs.
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Possible Mechanism for Blood Cancer Type
A new molecular mechanism may underlie a diverse group of blood cancers called myelodysplastic syndromes.
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