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To: Multiple recipients of list HUM-MOLGEN <HUM-MOLGEN@NIC.SURFNET.NL>
Subject: NEWS: in Bioscience and Medicine
From: Frank Zollmann <frank.zollmann@stud.uni-rostock.de>
Date: Fri, 10 Nov 1995 17:08:14 NFT-1MESZ
Organization: Rechenzentrum - Universitšt Rostock
Priority: normal

         HUM-MOLGEN News in Bioscience and Medicine


1 | The TIGR Human cDNA Database (HCD)
2 | An Open Access On-Line Breast Cancer Mutation Data Base
3 | American Heart Association journals online
4 | The FASEB Journal
5 | To: Members of the Congressional Liaison-Committee
    Re: NIH Funding Letter-Immediate Action Needed
6 | How to announce new Internet resources, press releases etc.


1  | The TIGR Human cDNA Database (HCD)

 The TIGR Human cDNA Database (HCD) provides researchers at
 non-profit institutions access to cDNA/EST sequence and related data
 from The Institute for Genomic Research (TIGR) and Human Genome
 Sciences (HGS). HCD is designed to promote research using these data
 while protecting intellectual property rights of their discoverers.
 In addition, ESTs from world-wide EST projects have been
 incorporated into HCD and are added to the database on a regular
 basis. The data are curated and maintained at The Institute for
 Genomic Research where the system is also operated and managed.

 An initial analysis of these data has been published (Initial
 assesment of human gene diversity and expression patterns based upon
 83 million nucleotides of cDNA sequence, Adams et al., Nature (1995)
 377(Suppl): 3-174). You may search the putative identifications of
 ESTs and THCs from the Nature Genome Directory.

 < http://www.tigr.org/tdb/hcd/hcd.html >
 < http://www.tigr.org/tdb/hcd/nature_paper/nature_paper.html >


2  | An Open Access On-Line Breast Cancer Mutation Data Base

 This Breast Cancer Information Core has been established to
 facilitate the detection and characterization of breast cancer
 susceptibility genes. It has been set up to be a repository for all
 mutations and polymorphisms in these genes. More importantly, it is
 meant to provide help in the form of techniques, primers, and
 support to those carrying out the lab work. By having access be
 through membership it is hoped that it will be a place where
 mutations found yet not necessarily already published can be
 accessible to others working in the field.

 < http://www.nchgr.nih.gov/dir/lab_transfer/bic/ >


3  | American Heart Association journals online

 The American Heart Association, one of the world's premier health
 organizations, is committed to reducing disability and death from
 cardiovascular diseases and stroke.

Art., Thromb., and Vasc. Bio.:
Circulation:   http://www.at-home.com/amhrt/CIRC/issues.html
Circulation Research:
Stroke:        http://www.at-home.com/amhrt/STROKE/issues.html
Hypertension:  http://www.at-home.com/amhrt/HYPER/issues.html


4  | The FASEB Journal

 owns his own WWW page (including TOC and abstracts). This service is
 part of the FASEB information services. The Federation of American
 Societies for Experimental Biologyhics is the largest coalition of
 life sciences societies in the United States, and represents over
 42,000 biomedical and biological scientists.

 < http://www.at-home.com/amhrt/HYPER/issues.html >
 < http://www.faseb.org/ >


5  | date: Tue, 7/Nov/1995 | E-mail: kathy@ascb.faseb.org

 November 8, 1995

 To: Members of the Congressional Liaison-Committee
 From: Joint Steering Committee for Public Policy
 Re: NIH Funding Letter-Immediate Action Needed


 In response to the current budget impasse, the
 co-chairs of the Congressional Biomedical Research
 Caucus circulated a "Dear Colleague" letter on the NIH
 budget situation. The letter was circulated by Reps.
 George Gekas (R-PA), Bill Richardson (D-NM), and Cliff
 Stearns (R-FL) and asks that the NIH be a top priority
 during budget negotiations and be funded at the highest
 possible level for FY'96.


 CLC members are asked to contact their Representatives
 now through December 1 to ask that they sign the "Dear
 Colleague" letter in support of increased funding for
 the NIH. Please call the Capitol switchboard (tel:
 202/224-3121) to connect to your Representative's
 office. Ask that the Congressman/woman contact Seth
 Johnson in Congressman Gekas' office at 202/225-4315.

 The following Members have already signed the "Dear
 Colleague" letter: Porter (R-IL), Coyne (D-PA),
 Nethercutt (R-WA), Klug (R-WI), Fowler (R-FL), Clayton
 (D-NC), Pallone (D-NJ), Bentsen (D-TX), Morella (R-MD),
 Cunningham (R-CA), Clayton (D-NC), Davis (R-VA), Fox
 (R-PA), Olver (D-MA), Maloney (D-NY), Hall (D-OH),
 DeFazio (D-OR), Frank (D-MA), Markey (D-MA), Dellums
 (D-CA), McDermott (D-WA), Meehan (D-MA), and Dingell

 Dear Colleague:

 We are deeply concerned that the 5.7% FY'96 funding
 increase for the National Institutes of Health (NIH)
 passed by the House may be permanently delayed by the
 application of an across the board funding formula in
 any Continuing Resolution for Appropriations (CR).
 Under the current operating CR until Nov. 13th, the NIH
 is now funded by a 5% decease in funds from the FY'95
 funding level.

 The NIH is a program that all parties in the budget
 negotiations-- the Administration, the House and Senate
 Appropriations Committees- -agreed was among the
 highest funding priorities for FY'96. It is
 foreseeable that the NIH may continue to be funded at
 the reduced level of 95% of last year's funds
 throughout FY'96. This would seriously jeopardize our
 progress in biomedical research and produce a result
 that no one supported.

 We are asking you to join us in the attached letter to
 President Clinton, Speaker Gingrich, Chairman
 Livingston, Senate Majority Leader Dole, and Chairman
 Hatfield. Please contact Seth Johnson at 225-4315 if
 you would like to sign on to the letter.

 George Gekas, Bill Richardson, Cliff Stearns

 Excerpts of the letter to be signed by your Member of
 Congress follow:


 We are concerned about the current funding situation
 for the NIH. The NIH. The NIH is a world leader in
 biomedical research. Its programs enjoy the broad
 bipartisan support of both the Congress and the
 American public. The Administration, as well as the
 House and Senate Appropriations Committees, all
 recommended FY'96 funding increases for the NIH, but
 the current CR reduces NIH funding to 95% of the FY'95
 funding level. This reduction is unnecessary to
 achieve a balanced budget since both the House and
 Senate Appropriations Committees recommended the NIH
 increase in the context of a seven-year balanced budget

 If the current CR's funding reduction for the NIH were
 to be continued beyond the November 13th expiration
 date in any future budget agreements, there will be
 serious consequences for the progress of biomedical
 research in the United States. The unintended
 consequences of across-the-board funding formulas with
 no budget priority decisions threaten future research
 efforts. Disease costs the nation billions every year
 in health care costs. As we strive to achieve a
 balanced budget, we must adopt policies and funding
 priorities that make the most of scarce federal
 dollars. Federal funding for biomedical research
 should be a top priority because without new strategies
 to prevent, intervene and treat diseases, health care
 costs will continue to spiral out of control.

 For example, last year the nation spent $90 billion on
 the care of the Alzheimer's patients. Significant
 progress through biomedical research to delay the most
 debilitating aspects of a disease requiring around the
 clock nursing care would save billions of Medicare and
 Medicaid dollars every year. An investment of one
 billion dollars in NIH research wuld be a bargain to
 save approximately $40 billion in federal health care
 costs. Currently, we fund only $300 millioon for NIH
 research on Alzheimer's disease. Adequate funding for
 the NIH not only saves scarce federal health care
 dollars, but also provides hope and solutions to the
 victims of diabetes, heart, stroke, and other chronic

 We strongly urge you to fund the National Institutes of
 Health in any budget agreement at the highest possible
 level for FY'96, consistent with the funding priorities
 set by the House and Senate Appropriations Committees
 and the Clinton Administration.

 (signed Member of Congress)

 * * *

 For more information, contact Jim Bernstein at the ASCB
 at 301/530-7153, or Pete Farnham at the ASBMB at


6 | How to announce new Internet resources, press releases etc.

 You can announce (free) new Internet resources, press releases etc.
 at  http://www.informatik.uni-rostock.de/HMB-NewsGen/vw3news?postF

 For other announcements please take a look at


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