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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - April 26, 2006
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Wed, 26 Apr 2006 13:57:29 +0200

__________________________________________________________________________

    RNAi Europe - Conference & Exhibition

    28-29 September 2006, Prague, Czech Republic

    => http://hum-molgen.org/promotion-RNAi
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - April 26, 2006 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L,
R. Nemade, D. Sharma, F.S. Zollmann
http://hum-molgen.org/NewsGen

- A Text-Mining Analysis Of The Human Phenome
    Scientists have used text mining to classify over 5000 human
    phenotypes contained in the Online Mendelian Inheritance in Man
    database.
    http://hum-molgen.org/NewsGen/04-2006/msg41.html

- Schizophrenia Genetics: Uncovering Positional Candidate Genes
    Reports outlines the evidence supporting each of the proposed
    positional candidate genes.
    http://hum-molgen.org/NewsGen/04-2006/msg39.html

- A Novel Mutation In JARID1C Gene Associated With Mental Retardation
    Report presents results obtained by screening the JARID1C gene in 24
    mentally retarded males with history of at least two affected males.
    http://hum-molgen.org/NewsGen/04-2006/msg38.html

- Neural Effects Of Cocaine Withdrawal
    Scientists describe a mechanism in the brain that may contribute to
    the cue-triggered drug seeking during abstinence.
    http://hum-molgen.org/NewsGen/04-2006/msg37.html

- Teaching Transplant Tolerance
    Study explains how specific immune cells help to make transplanted
    donor tissue 'tolerable'.
    http://hum-molgen.org/NewsGen/04-2006/msg36.html

- Natural Memory
    Natural killer (NK) cells, an important component of the immune
    system, can 'remember' prior exposure to foreign molecules.
    http://hum-molgen.org/NewsGen/04-2006/msg35.html

- Genome Wide Profiling Of Chromatin Elements
    A new study reports the binding profile of proteins involved in
    organizing the structure of DNA in the Drosophila genome.
    http://hum-molgen.org/NewsGen/04-2006/msg34.html

- New Link To Insulin Sensitization
    A new component involved in the regulation of an adipose-tissue
    hormone linked to insulin action.
    http://hum-molgen.org/NewsGen/04-2006/msg33.html

- Better Detection To Tackle Bioterrorism
    Scientists have developed a test that is at least a thousand times
    more sensitive than the best current approaches for detecting in the
    field trace quantities of cholera and botulinum toxins.
    http://hum-molgen.org/NewsGen/04-2006/msg32.html

- Stem Cells And Leukaemia
    Study shows that a signalling molecule known as phosphatase and
    tensin homologue, or PTEN,is crucial in keeping in balance the normal
    expansion of cell numbers in the bone marrow proliferation pathway.
    http://hum-molgen.org/NewsGen/04-2006/msg31.html

- Regular Recycling Saves Lives
    Two research papers suggest that the process of protein degradation
    and clearance of cellular components may be more important in
    maintaining the nervous system and keeping neurodegeneration at bay
    than was previously understood.
    http://hum-molgen.org/NewsGen/04-2006/msg30.html

- Keeping Stem Cells In Check
    A group of proteins has been shown to help hold the reins on
    embryonic stem (ES) cell differentiation.
    http://hum-molgen.org/NewsGen/04-2006/msg29.html

- Metabolic Phenotype Predicts Drug Response
    European team proposes a new way to personalize drug therapy based on
    a patient's metabolic phenotype.
    http://hum-molgen.org/NewsGen/04-2006/msg28.html

- Evading The Immune System To Deliver Viral Antibodies
    A virus that shows promise as a means of vaccine delivery of HIV-1
    antigens could be altered to become effective in a larger portion of
    the population.
    http://hum-molgen.org/NewsGen/04-2006/msg27.html

- Triggering Insulin Resistance
    Study identifies reactive oxygen species as key players in the
    development of insulin resistance.
    http://hum-molgen.org/NewsGen/04-2006/msg26.html

- Identifying The Function Of p110-alpha AOP
    One form of the enzyme p110-alpha PI(3)K is vital for cell growth and
    metabolism.
    http://hum-molgen.org/NewsGen/04-2006/msg25.html

- A Matter Of Taste
    An identical variability in taste sensitivity evolved independently
    in chimpanzees and humans.
    http://hum-molgen.org/NewsGen/04-2006/msg24.html

- Minimal Cocktail For Growing Human Embryonic Stem Cells Established
    hESC cocktail contains only purified recombinant,
    chemically-synthesized, or purified human factors to support the cell
    growth
    http://hum-molgen.org/NewsGen/04-2006/msg23.html

- Gene Variant Protects Against Type 2 Diabetes, Heart Disease, And
   Hypertriglyceridemia
    Identification of variant indicates that aP2 might play a similar
    role in humans as it does in mice
    http://hum-molgen.org/NewsGen/04-2006/msg22.html

- Study Holds Promise For A New Approach To Drug Therapy
    Differential targeting of Gbetagamma-subunit signaling with small
    molecules
    http://hum-molgen.org/NewsGen/04-2006/msg21.html

- New Mechanism for Essential Genome-Wide Gene Silencing Identified
    Histone sumoylation is a negative regulator in Saccharomyces
    cerevisiae and shows dynamic interplay with positive-acting histone
    modifications
    http://hum-molgen.org/NewsGen/04-2006/msg20.html

- Blood Pressure Medication May Revolutionize Treatment Of Marfan
   Syndrome
    Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse
    model of Marfan syndrome
    http://hum-molgen.org/NewsGen/04-2006/msg19.html

- Polycomb Regulation of Embryonic Stem Cell Differentiation
    Polycomb group proteins play a key role in regulating vertebrate
    embryogenesis and in maintaining stem cell pluripotency.
    http://hum-molgen.org/NewsGen/04-2006/msg18.html

- Apes and ApoB: systemic silencing
    RNAi steps closer to a clinically relevant therapy with positive
    outcomes in a non-human primate study via systemic delivery.
    http://hum-molgen.org/NewsGen/04-2006/msg17.html

- Drug addiction: a hit from the genes
    Yale School of Medicine researchers have identified a genetic linkage
    for dependence on drugs such as heroin, morphine and oxycontin.
    http://hum-molgen.org/NewsGen/04-2006/msg16.html

- Switching: a light on gene regulation
    Scientists have released a map of regions in the human genome that
    work as switches for gene regulation.
    http://hum-molgen.org/NewsGen/04-2006/msg15.html

- Contact Genetic News editors
    WWW: http://hum-molgen.org/editors.html
    E-mail: news@hum-molgen.org


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http://hum-molgen.org/positions/

- Biochemistry / Immunology: Sales
    Shanghai Hanhong Chemical Co., Ltd., Shanghai, 200237, China
    http://hum-molgen.org/positions/assistant/0175.html

- Biotechnology: POST-DOCTORAL FELLOWSHIP
    INRA - Mammalian embryo nuclear architecture, Jouy en Josas, 78350,
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Literature
http://hum-molgen.org/literature/

- Cold Spring Harbor Laboratory Press to Launch CSH Protocols
    Community-Driven, Interactive Methods Database set for release June,
    2006
    http://hum-molgen.org/literature/04-2006/msg01.html


Biotechnical requests and sources
http://hum-molgen.org/biotechnology


Events in bioscience and medicine
http://hum-molgen.org/meetings/

- Post event (free)
   http://hum-molgen.de/cgi-bin/meetings.pl?login


Registry of Biomedical Companies (1274 active entries)
http://hum-molgen.org/companies/


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Feedback
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Advertise at HUM-MOLGEN
http://hum-molgen.org/flyer/advertise.pdf
contact FS Zollmann (dialogue@hum-molgen.org)

__________________________________________________________________________

    RNAi Europe - Conference & Exhibition

    28-29 September 2006, Prague, Czech Republic

    => http://hum-molgen.org/promotion-RNAi
__________________________________________________________________________ 





   
 
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