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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - May 24, 2006
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Wed, 24 May 2006 13:58:18 +0200

__________________________________________________________________________

    RNAi Europe - Conference & Exhibition

    28-29 September 2006, Prague, Czech Republic

    => http://hum-molgen.org/promotion-RNAi
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - May 24, 2006 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L,
R. Nemade, D. Sharma, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Inducible Regulation Of Runx2-Stimulated Osteogenesis
    Researchers describe a retroviral system to deliver the Runx2
    osteoblastic transcription factor.
    http://hum-molgen.org/NewsGen/05-2006/msg40.html

- Mosaic Vectors For Efficient Vector Purification And Targeting To
   Vascular Endothelial Cells
    Adeno-associated virus (AAV) 1 has shown the most promise among the
    AAV vectors for the transduction of vascular endothelial cells.
    http://hum-molgen.org/NewsGen/05-2006/msg39.html

- RNAi Therapeutics: Can siRNAs Conquer SARS?
    Report on a new approach to coping with emerging infectious diseases,
    that uses small interfering (si)RNAs.
    http://hum-molgen.org/NewsGen/05-2006/msg38.html

- Regeneration Of Injured Optic Nerve
    A treatment applied three days after optic nerve injury greatly
    improves regeneration.
    http://hum-molgen.org/NewsGen/05-2006/msg37.html

- New Techniques For Chromosomal Damage Control
    Two articles describe tools for the detection of large-scale
    structural rearrangements in individual chromosomes.
    http://hum-molgen.org/NewsGen/05-2006/msg36.html

- Gene Variant Associated With Type 1 Diabetes
    A new gene variant associated with risk of type 1 diabetes is
    reported.
    http://hum-molgen.org/NewsGen/05-2006/msg35.html

- Mothballs Link Cell Death And Cancer
    Components of the humble mothball are carcinogens because they block
    cell suicide.
    http://hum-molgen.org/NewsGen/05-2006/msg34.html

- SUMO Switches Metastasis On And Off
    New players in the process of metastasis of cancer cells are
    described.
    http://hum-molgen.org/NewsGen/05-2006/msg33.html

- Immune Molecule Fuels Tumours
    A molecule central to chronic autoimmune diseases also promotes the
    incidence and growth of tumours.
    http://hum-molgen.org/NewsGen/05-2006/msg32.html

- Chromosome 1 Completes The Set
    Report on the finished DNA sequence of human chromosome 1.
    http://hum-molgen.org/NewsGen/05-2006/msg31.html

- Novel Antibiotic Fights Hospital Killers
    Team of researchers discovers a potent natural antibiotic that kills
    many Gram-positive bacteria.
    http://hum-molgen.org/NewsGen/05-2006/msg30.html

- A New Signal For Axon Regeneration Is Discovered
    Oncomodulin, released from macrophages, stimulates axon regeneration
    as part of the response to optic nerve injury.
    http://hum-molgen.org/NewsGen/05-2006/msg29.html

- The next generation of interferons needs improvement in efficacy and
   safety
    The interferon alpha market is smaller than the interferon beta
    market, but is characterized by far more products and R&D projects.
    http://hum-molgen.org/NewsGen/05-2006/msg28.html

- Tumor Stem Cells Turn Out to be Good Models for Brain Tumor Research
    Glioblastoma tumor stem cell lines offer a powerful new tool for
    research and treatment.
    http://hum-molgen.org/NewsGen/05-2006/msg27.html

- Prozac's Target Revealed
    Neural stem cells provide information about how cells become reactive
    to Prozac (fluoxetine).
    http://hum-molgen.org/NewsGen/05-2006/msg25.html

- A Loose Fit May Be The Best Bet In Drug Design
    Common wisdom challenged as loosely connecting ligands at receptor
    sites lead to better signalling.
    http://hum-molgen.org/NewsGen/05-2006/msg26.html

- Total-Genome Analysis of BRCA1/2-Related Invasive Carcinomas of the
   Breast Identifies Tumor Stroma as Potential Landscaper for Neoplastic
   Initiation
    Authors postulate that such a genetically unstable stroma might
    facilitate a microenvironment that may subsequently lead to
    neoplastic transformation.
    http://hum-molgen.org/NewsGen/05-2006/msg24.html

- ELMOD2 Is A Candidate Gene For Familial Idiopathic Pulmonary Fibrosis
    Research suggests ELMOD2 as a novel candidate gene for susceptibility
    in familial IPF.
    http://hum-molgen.org/NewsGen/05-2006/msg23.html

- Human Genomic Deletions Mediated By Recombination Between Alu Elements
    Scientists compare the reference human and chimpanzee genomes to
    determine the magnitude of this recombination process in the human
    lineage.
    http://hum-molgen.org/NewsGen/05-2006/msg21.html

- Promoter Mutations That Increase Amyloid Precursor-Protein Expression
   Are Associated with Alzheimer Disease
    The present study provides evidence that Amyloid Precursor-Protein
    (APP)-promoter mutations that significantly increase APP expression
    levels are associated with Alzheimer disease.
    http://hum-molgen.org/NewsGen/05-2006/msg20.html

- Diabetes Gene At Root Of Wider Syndrome
    Study shows that some of the 'Gain of function' gene mutations
    associated with neonatal diabetes mutations can cause a syndrome that
    can include developmental delay, epilepsy and muscle weakness.
    http://hum-molgen.org/NewsGen/05-2006/msg19.html

- Old Drug, New Target
    Scientists have identified a new target for an old drug that has been
    used to treat tuberculosis for over 50 years
    http://hum-molgen.org/NewsGen/05-2006/msg18.html

- Better Digs Benefit Behavior: New Neurons Not Required
    A new study fails to find a causal relationship between behavioral
    improvements and increased neurogenesis in adult mice.
    http://hum-molgen.org/NewsGen/05-2006/msg17.html

- Sensing Bacterial Infection
    New information on the complex interplay between host cells and
    bacteria during infection is reported.
    http://hum-molgen.org/NewsGen/05-2006/msg16.html

- Common Genetic Variant Associated With Prostate Cancer
    A common genetic marker that is found more frequently in men with
    prostate cancer than those without is reported in a study.
    http://hum-molgen.org/NewsGen/05-2006/msg15.html

- Nuclear Protein Controls Virus Invasion
    A protein in the cell's nuclear membrane regulates the ability of the
    HIV virus to invade human cells.
    http://hum-molgen.org/NewsGen/05-2006/msg14.html

- Parkinson's Gene Cripples Mitochondria
    Two teams of scientists reveal that a mutant protein implicated in
    inherited Parkinson's disease disables the cell's mitochondria.
    http://hum-molgen.org/NewsGen/05-2006/msg13.html

- LOX Stops The Spread
    Scientists identify a protein vital for metastasis that could be a
    new target for cancer therapies.
    http://hum-molgen.org/NewsGen/05-2006/msg12.html

- Not Without Risk
    A gene-therapy treatment for a severe immune deficiency could
    contribute to the later development of T-cell lymphomas.
    http://hum-molgen.org/NewsGen/05-2006/msg11.html

- Contact Genetic News editors
    WWW: http://hum-molgen.org/editors.html
    E-mail: news@hum-molgen.org


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__________________________________________________________________________

    RNAi Europe - Conference & Exhibition

    28-29 September 2006, Prague, Czech Republic

    => http://hum-molgen.org/promotion-RNAi
__________________________________________________________________________ 





   
 
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