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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - October 13, 2006
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Fri, 13 Oct 2006 13:58:52 +0200

__________________________________________________________________________

   2nd Modern Drug Discovery and Development Summit (M3D)
   December 4-6, 2006 - Philadelphia, PA

   - Learn from over 250 expert speakers
   - Attend 11 full conferences at 1 venue
   - View numerous cutting edge posters
   - Network with a few thousand of your peers
   - Establish key business ties with executives
     and scientists dedicated to drug discovery

   Visit http://gtcbio.com/confpage.asp?cid=8 for more information
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - October 13, 2006 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L,
R. Nemade, D. Sharma, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Detecting Disease-Causing Mutations in the Human Genome by Haplotype
  Matching
   The authors describe a new strategy for detecting mutations that is
   based on comparing affected haplotypes with closely matched control
   sequences from healthy individuals, rather than with the human
   reference genome.
   http://hum-molgen.org/NewsGen/10-2006/msg17.html

- PLA2G6 Mutation Underlies Infantile Neuroaxonal Dystrophy
   The study findings highlight a role of phospholipase in
   neurodegenerative disorders.
   http://hum-molgen.org/NewsGen/10-2006/msg16.html

- A Novel Mutation in FGFR3 Causes Camptodactyly, Tall Stature, and
  Hearing Loss (CATSHL) Syndrome
   Abnormal FGFR3 signaling can cause human anomalies by promoting as
   well as inhibiting endochondral bone growth.
   http://hum-molgen.org/NewsGen/10-2006/msg15.html

- Systems Biology Tackles The Mechanisms Of Cancer
   Potential novel targets for anti-cancer therapy are revealed.
   http://hum-molgen.org/NewsGen/10-2006/msg14.html

- Itching And Scratching
   Dust mites produce an allergen that disrupts the skin's ability to
   act as a barrier to other allergens and environmental irritants.
   http://hum-molgen.org/NewsGen/10-2006/msg13.html

- Recommendations Help Identify Patients Suitable For NSAID Treatment
   Recommendations should help physicians to identify quickly whether or
   not a patient is suitable for treatment with nonsteroidal
   anti-inflammatory drugs (NSAIDs).
   http://hum-molgen.org/NewsGen/10-2006/msg12.html

- Focus On Childhood Developmental Disorders
   A special focus issue on childhood developmental disorders, including
   specific language impairment and dyslexia, autism, and the mental
   retardation syndrome fragile X, is presented.
   http://hum-molgen.org/NewsGen/10-2006/msg11.html

- New Strategy For Controlling Inflammation
   A previously unknown method of terminating immune responses is
   reported.
   http://hum-molgen.org/NewsGen/10-2006/msg10.html

- New Breast Cancer Susceptibility Gene Identified
   Women with mutations in a gene called BRIP1 have twice the normal
   risk of breast cancer.
   http://hum-molgen.org/NewsGen/10-2006/msg09.html

- One Step Toward More Efficient Cloning
   A one-step somatic cell nuclear transfer procedure using a
   differentiated cell as a nuclear donor is reported for the first
   time.
   http://hum-molgen.org/NewsGen/10-2006/msg08.html

- Controlling The Insulin-Degrading Enzyme May Relieve Alzheimer's
  Disease
   The structure of an enzyme that degrades insulin and amyloid-beta
   suggests a possible way to design drugs that combat the abnormal
   levels of these proteins in sufferers of diabetes or Alzheimer's
   disease.
   http://hum-molgen.org/NewsGen/10-2006/msg07.html

- Drug Target For Obesity?
   A molecule that makes mammals feel full up has been identified.
   http://hum-molgen.org/NewsGen/10-2006/msg06.html

- Potential Cure for Type 1 Diabetes in Islet Transplantation
    Clinical Trial Shows Islet Transplantation is a Promising Procedure
    For Certain Patients with Severe Type 1 Diabetes
    http://hum-molgen.org/NewsGen/10-2006/msg05.html

- H9N2 Avian Flu Vaccine Paired with Adjuvant Provokes Strong Human
   Immune Response
    Clinical trial reports that when combined with an adjuvant, low doses
    of an experimental vaccine against a strain of avian influenza (H9N2)
    provoked a strong antibody response in human volunteers.
    http://hum-molgen.org/NewsGen/10-2006/msg04.html

- Another Gene Implicated in Cleft Lip and Palate
    Underexpression of SUMO1 can cause the world's most common birth
    defect, cleft lip and palate.
    http://hum-molgen.org/NewsGen/10-2006/msg03.html

- Connectivity Map
    Using gene-expression signatures to connect small molecules, genes,
    and disease
    http://hum-molgen.org/NewsGen/10-2006/msg02.html

- Jumping gene could provide non-viral alternative for gene therapy
    piggyBac is a flexible and highly active transposon as compared to
    Sleeping Beauty, Tol2, and Mos1 in mammalian cells
    http://hum-molgen.org/NewsGen/10-2006/msg01.html

- Contact Genetic News editors
    WWW: http://hum-molgen.org/editors.html
    E-mail: news@hum-molgen.org


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    contact admin@hum-molgen.org


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Advertise at HUM-MOLGEN
http://hum-molgen.org/flyer/advertise.pdf
contact FS Zollmann (dialogue@hum-molgen.org)

__________________________________________________________________________

   2nd Modern Drug Discovery and Development Summit (M3D)
   December 4-6, 2006 - Philadelphia, PA

   - Learn from over 250 expert speakers
   - Attend 11 full conferences at 1 venue
   - View numerous cutting edge posters
   - Network with a few thousand of your peers
   - Establish key business ties with executives
     and scientists dedicated to drug discovery

   Visit http://gtcbio.com/confpage.asp?cid=8 for more information
__________________________________________________________________________

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| INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
| HUM-MOLGEN - http://hum-molgen.org
| (C) 1994-2006





   
 
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