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Euroscicon, The Royal College of Pathologists, 2 Carlton House Terrace , London, UK
Wednesday, 05 June 2013
http://www.regonline.co.uk/Regen2013
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Organized by:
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Euroscicon |
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Invited Speakers:
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Talks include
3-Dimensional Culture Models of Joint Tissues: Applications in Tissue Engineering and Arthritis Research
Dr Ali Mobasheri, Associate Professor and Reader in Comparative Physiology, University of Nottingham, UK
This presentation will focus on some of the most popular in vitro models that have been developed for cartilage tissue engineering. Many in vitro models can be used as drug screening systems and as culture models for studying the biology of cartilage and the pathophysiology of joint disease. This presentation will also highlight the fact that regenerative medicine and tissue engineering have important consequences for animal research and can be exploited to develop powerful animal sparing in vitro models. Refining these models will advance tissue engineering and regenerative medicine and may significantly reduce our dependence on animals in research.
Steps towards Physiological simulation of Dental Tissues
Dr Reem El-Gendy, Leeds Dental Institute
Immunocompetent models of human respiratory epithelium
Dr Amir Ghaem-Maghami, Nottingham University
Despite enhanced patient care, the morbidity and mortality of patients with lung disease have remained high. This is partly due to lack of efficient therapeutic strategies and also that a large proportion of patients do not respond to treatments. There is a lack of predictive preclinical models of asthma and new treatments that enter clinical trials frequently fail, possibly because preclinical animal studies are often limited in their physiological relevance to the human lung. To address some of these issues we are developing a physiologically relevant immune responsive 3D model of human lung that can be used for drug assessment and disease modelling.
Bone regenerating ceramic materials
Professor Joost de Bruijn, Professor of Biomaterials, School of Engineering and Materials Science, QMUL, UK
The use of growth factors or progenitor/stem cells for functional bone tissue regeneration have received much attention as potential alternatives to autologous bone grafting in the past decades. Some of the hurdles to overcome in these technologies include ensuring cell survival with the cell therapy approach and using potent but less supra-physiological concentrations of growth factors to minimize adverse reactions. To circumvent the necessity of cells or growth factors in bone tissue regeneration, we have developed a micro/nanostructured calcium phosphate ceramic that is capable of inducing bone formation without the necessity of adding cells or growth factors. These osteoinductive ceramics have shown excellent bone regeneration potential of large, critical sized bone defects. In this talk, an overview will be provided of the research performed in various pre-clinical and clinical case studies on this new group of bone regenerating ceramics.
Additional Speakers
Dr Andrew Hopkinson
Queen's Medical Centre
Eye & ENT Centre
Nottingham
United Kingdom Dr Paolo De Coppi, MD, PhD
Clinical Senior Lecturer and Consultant
Surgery Unit, UCL Institute of Child Health and Great Ormond Street Hospital Professor Sandra Downes
Manchester University
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Deadline for Abstracts:
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March 10th 2013
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Registration:
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A late registration fee applies after March 20th 2013. After this time the fees double, so make sure you register early! http://www.regonline.co.uk/Regen2013
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E-mail:
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astrid.englezou@euroscicon.com
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