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Headspace Gas Ingress Methods: The Golden Tool for Container Closure Integrity Testing

 
  June 21, 2023  
     
 
Xtalks, online
2023 -7-25


Historically, good container closure integrity (CCI) has been linked to the maintenance of sterility. A container that loses, or does not have, good closure integrity is at risk for microbial contamination.
 
However, the context of container closure integrity has become broader over the years. An increasing number of formulations have significant sensitivity to oxygen and need to be packaged under an inert atmosphere. A freeze-dried product requires protection against water vapor and is often packaged in a partial vacuum to help with reconstitution and/or sealing of the stopper.
 
In these cases, good container closure integrity is necessary not only for the maintenance of sterility but also to maintain critical headspace gas conditions. Note that, quite generally, a container that is gas-tight will also be tight against microbial ingress. Therefore, the requirement to maintain headspace gas conditions imposes higher standards on CCI than the requirement to maintain sterility.
 
Join this webinar to discover the importance of container closure integrity and the role of headspace gas ingress methods. Learn how maintaining critical headspace gas conditions ensures product stability and safety.
 
REFERENCES:
 
 
Organized by: Xtalks
Invited Speakers: Dr. Derek Duncan, PhD, Director, Lighthouse Instruments
 
Deadline for Abstracts: 2023 -7-25
 
Registration: Free registration
E-mail: ajuurinen@xtalks.com
 
   
 
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