|
|
A profiling system predicts well the clinical outcome of the most common type of childhood malignant brain tumour (medulloblastoma), report Todd R. Golub of the Massachusetts Institute of Technology, Cambridge, and colleagues in this week's Nature (Vol. 415, No. 6870, 24 January 2002).
Little is known about early-childhood central nervous system tumours. Their diagnosis, on the basis of appearance alone, is controversial and patients' response to therapy has to date been difficult to predict. So Golub's team has developed a classification system based on DNA microarray gene expression data that demonstrates that medulloblastomas are molecularly distinct from other tumours and that sheds some light on why they may occur. "This work illustrates how genomic technologies have the potential to advance treatment towards a more individualised approach to medicine," the researchers conclude. CONTACT: Todd R. Golub tel +1 617 632 4903 e-mail golub@genome.wi.mit.edu (C) Nature press release.
Message posted by: Trevor M. D'Souza
|
|
Variants Associated with Pediatric Allergic Disorder
Mutations in PHF6 Found in T-Cell Leukemia
Genetic Risk Variant for Urinary Bladder Cancer
Antibody Has Therapeutic Effect on Mice with ALS
Regulating P53 Activity in Cancer Cells
Anti-RNA Therapy Counters Breast Cancer Spread
Mitochondrial DNA Diversity
The Power of RNA Sequencing
‘Pro-Ageing' Therapy for Cancer?
Niche Genetics Influence Leukaemia
Molecular Biology: Clinical Promise for RNA Interference
Chemoprevention Cocktail for Colon Cancer
more news ...
|